Efficacies of percutaneous vertebral angioplasty, percutaneous kyphoplasty and conventional open operation in the treatment of spinal tumor

Objective: To compare the efficacies of percutaneous vertebral angioplasty (PVP), percutaneous kyphoplasty (PKP) and conventional open operation in the treatment of spinal tumor. Methods: Forty-seven patients who admitted to our hospital were divided into three groups: PVP group (treated with PVP), PKP group (treated with PKP) and control group (treated with conventional open operation). Visual analogue scales (VAS), Karnofsky Performance Status (KPS) and numerical rating scale (NRS) score were scoring methods within different groups, and X-ray examination, recurrence rate of postoperative pain, complications and other indicators were indicators for the comparisons between groups. The average follow-up period was 3~24 months with the average time of (17.61 ± 3.96) months. Results: Three months after operation, the total effective rate of PVP, PKP and control group was 86.7%, 94.4%, 57.1%, respectively, and the efficacies in the PVP group and PKP group were significantly better than that in the control group (both P < 0.05). All patients had significantly lower VAS score, lower NRS score and higher KPS score after the treatment compared with those before the treatment (all P < 0.01). Patients underwent PVP and PKP showed that the height of the vertebral body was not collapsed by X-ray examination. There were significant differences for the total recurrence rates between the PKP group and the control group, as well as between the PKP group and the PVP group (both P < 0.05). There were significant differences for bone cement leakage rates between the PKP group and the control group, and between the PKP group and the PVP group (both P < 0.05). The survival rates had significant differences between the control group and the PVP group (P = 0.045), as well as between the control group and the PKP group (P = 0.035). Conclusion: PVP and PKP can effectively relieve the pain of patients with spinal tumor, and PKP can significantly reduce the complications of bone cement leakage under the premise of ensuring the operation effect.